Systematic Reviews
Quality Assessment
- Standard quality assessment criteriaStandard quality assessment criteria for evaluating primary research papers from a variety of fields.
Prepared by: Kmet, L.M., Lee, R.C. & Cook, L.S.
Alberta Heritage Foundation for Medical Research, 2004.
Contents includes: Table 1: Checklist for assessing the quality of quantitative studies Table 2: Checklist for assessing the quality of qualitative studies (QualSyst Tool) - QUADAS-2QUADAS - a quality assessment tool for diagnostic accuracy studies.
QUADAS is recommended for use in systematic reviews to evaluate the risk of bias and applicability of primary diagnostic accuracy studies - Assessing the Quality of Individual StudiesThe Agency for Healthcare Research and Quality (AHRQ)
Training Modules for Systematic Reviews Methods Guide
Workshop presentation that focuses on quality assessment of studies for reviews.
Other Quality Assessment Resources
- GRADE - Grading of Recommendations Assessment, Development and Evaluation
- JADAD - Jadad quality assessment scale for rating Randomized Controlled Trials
- Cochrane review form (see page 12 for Quality assessment)
- NOS - Newcastle-Ottawa quality assessment scale for case-control studies
- AHRQ checklist for Risk of Bias assessment in Comparative Effectiveness Reviews
- CHEC-list for methodological quality in Cost Effectiveness Analyses & Comparative Effectiveness Reviews
- AGREE-II Appraisal of Guidelines for Research and Evaluation
- AMSTAR - A Measurement Tool to Assess Systematic Reviews
- Mixed Methods Appraisal Tool - MMATThe MMAT is intended to be used as a checklist for concomitantly appraising and/or describing studies included in systematic mixed studies reviews (reviews including original qualitative, quantitative and mixed methods studies).
- STROBE checklistsFor observational studies
Critical Appraisal Resources
- Center for Evidence Based Medicine (CEBM)The Centre for Evidence-Based Medicine in Oxford (UK) provides tools to develop, teach and promote evidence-based health care. Their site provides useful tools and downloads for the critical appraisal of medical evidence. Example appraisal sheets are provided together with several helpful examples.
- Critical Appraisal Skills ProgramThe Critical Appraisal Skills Programme (CASP) helps people to find and interpret the best available evidence from health research.
- Joanna Briggs RAPid Assessment ProtocolThe JBI Rapid Assessment Protocol internet database (JBI RAPid) is an online training resource that provides a framework for critical appraisal of research papers using established data collection tools. RAPid has been designed to assist individual practitioners or students to acquire the skills of posing relevant questions about the feasibility, appropriateness, meaningfulness of an intervention or professional activity. (Requires registration with JBI)
Assessing Bias
- Cochrane HandbookPart 2 - Chapter 8
Assessing Risk of Bias in Included Studies - AHQRAssessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions
This is a chapter from the methods guide, "Methods Guide for Effectiveness and Comparative Effectiveness Reviews."
Quality Assessment Articles
Sanderson, S., Tatt, I. D., & Higgins, J. P. (2007). Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography. International journal of epidemiology, 36(3), 666-676.
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